Recent news has revealed that CaaMTech, a cannabinoid laboratory, has been doing extensive research on combining cannabis cannabinoids and psilocybin into an effective fusion for physical and mental health. The potential for new products with the ability to fight off cancers, a one-time stop remedy for many mental illnesses, inflammation reducer, and many other great benefits is within reach.
In a recent article from MJBizDaily they interviewed various prominent people in the industry. One interview was Charlie Bowman, the president and CEO of a Canadian cannabis company called Hexo Corp. He pointed out that the ability to combine certain cannabinoids like cannabichromene (CBC) which is hard to grow and synthesize, can help to reduce the price point for customers and consumers. This would be possible by turning the CBC into a water soluble form, combine it with the mushrooms, and then consume it as a tea for example.
How Does this Combination Work?
From multiple different studies, it is being discovered that the combination of cannabis and psilocybin can cross their effects on each other’s receptors. For example, cannabinoids only activate CB1 and CB2 receptors and psilocybin activates serotonin 2A receptors 5-HT2Ars, but when used together cannabinoids have been having more effects due to the serotonin receptor being active. One such study evaluating this was done by Spanish Scientists that discovered that cannabidiol (CBD) had neuroprotective and behavioral effects on hypoxic-ischemic piglets. Their conclusion stated that CBD prevented HI-induced mood disturbances in newborn piglets by acting on 5HT1AR activation and that it was needed for the CBD to have its neuroprotective effects.
Currently there is still much more research needed to figure out the combination and strengths of both cannabis and psilocybin. With the rise of various cannabinoids such as THC-P, THC-H, THC-JD, and others that have a more potent psychoactive effect than THC, these new cannabinoids could be a major key into discovering why psilocybin and other psychedelics are effective at healing the brain as well as work as a good combination.
Fusion Breakdown
Psilocybin has shown to have promising therapeutic benefits just on its own. Various studies have shown strong evidence that large doses of psilocybin were able to majorly decrease depression and anxiety in those receiving treatment for cancer. The results were so profound that it was noted that this result cannot be achieved in psychiatry. Along with that there was evidence to suggest that it could majorly help in addiction recovery. Further it’s stated that the potential to be a solution for relieving pain and ailments from various disorders are all on the table, but more research is needed.
Across all cannabinoids there are various therapeutic benefits. In general, most of them help with epilepsy, inflammation, pain relief, sleep aid, relaxing, nausea, depression, and anxiety. There is a theory called the Entourage Effect that using the full organic compounds of cannabis synergizes multiple cannabinoids, terpenes, and other compounds to maximize and strengthen their effects. This concept is essentially the same being explored with psilocybin being added in the mix.
With the ability of the specific 2A receptors 5-HT2Ars being activated by psilocybin the effects of cannabinoids may be so maximized that the therapeutic effects of them may become so common place that federal back and approved medicines could be coming to the market relatively soon.
The future is looking quite promising, and this discovery would be monumental as it would pull more people off synthetic and typically double edged sword pharmaceuticals that have failed to remedy many mental illnesses and other ailments.
